Disease-gene associations mined from literature

Literature associating MAP2K2 and Noonan syndrome with multiple lentigines

MAP2K2 [ENSP00000262948]

Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).

Synonyms:  MAP2K2,  MAP2K2p,  hMAP2K2,  B3KS97,  G5E9C7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM