DISEASES

Disease-gene associations mined from literature

Literature associating KCNQ4 and autosomal dominant nonsyndromic deafness 2A

KCNQ4 [ENSP00000262916]

Potassium voltage-gated channel, KQT-like subfamily, member 4; Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors; Deafness associated genes

Synonyms:  KCNQ4,  KCNQ4p,  hKCNQ4,  P56696,  P56696p ...

Linkouts:  STRING  Pharos  UniProt  OMIM