Disease-gene associations mined from literature

Literature associating XRCC1 and breast disease

XRCC1 [ENSP00000262887]

X-ray repair complementing defective repair in Chinese hamster cells 1; Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP-ribosyltransferase PARP1 activity.

Synonyms:  XRCC1,  XRCC1p,  hXRCC1,  M0QYS5,  M0R0D2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM