DISEASES

Disease-gene associations mined from literature

Literature associating TIMP2 and fibrosarcoma

TIMP2 [ENSP00000262768]

Tissue inhibitor of metalloproteinases 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19; Belongs to the protease inhibitor I35 (TIMP) family.

Synonyms:  TIMP2,  TIMP2p,  hTIMP2,  B4DFW2,  K7EIX4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM