DISEASES

Disease-gene associations mined from literature

Literature associating RHEB and kidney angiomyolipoma

RHEB [ENSP00000262187]

Ras homolog enriched in brain; Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity; RAS type GTPase family

Synonyms:  RHEB,  C9J931,  F8WBL3,  Q15382,  RHEB-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM