DISEASES

Disease-gene associations mined from literature

Literature associating MTUS1 and hepatocellular carcinoma

MTUS1 [ENSP00000262102]

Angiotensin-II type 2 receptor-interacting protein; Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth; Belongs to the MTUS1 family.

Synonyms:  MTUS1,  MTUS1p,  hMTUS1,  B4E246,  Q9ULD2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM