Literature associating MTUS1 and hepatocellular carcinoma
Angiotensin-II type 2 receptor-interacting protein; Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth; Belongs to the MTUS1 family.
Synonyms: MTUS1, MTUS1p, hMTUS1, B4E246, Q9ULD2 ...