Disease-gene associations mined from literature

Literature associating ATF1 and Ewing sarcoma

ATF1 [ENSP00000262053]

Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation; Basic leucine zipper proteins

Synonyms:  ATF1,  ATF1p,  hATF1,  B4DRF9,  F8VRN2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM