Disease-gene associations mined from literature

Literature associating FAF2 and dermatitis

FAF2 [ENSP00000261942]

Fas associated factor family member 2; Plays an important role in endoplasmic reticulum- associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis; UBX domain containing

Synonyms:  FAF2,  FAF2p,  hFAF2,  D6RBG6,  Q96CS3 ...

Linkouts:  STRING  Pharos  UniProt