Literature associating SEMA7A and esotropia
Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes; Belongs to the semaphorin family.
Synonyms: SEMA7A, SEMA7Ap, hSEMA7A, B3KMH6, F5GYX3 ...