Literature associating PARP16 and ARC syndrome
ADP-ribosyltransferase diphtheria toxin-like 15; Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those processes. May play a role in the unfolded protein response (UPR), by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono- ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine, cysteine or glutamate residues compared to other mono-ADP- ribosyltransferases; Poly(ADP-ribose) polymerases
Synonyms: PARP16, PARP16p, hPARP16, A0A024R5Y7, Q8N5Y8 ...