DISEASES

Disease-gene associations mined from literature

Literature associating CDH1 and breast cystic hypersecretory carcinoma

CDH1 [ENSP00000261769]

Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Synonyms:  CDH1,  CDH1p,  hCDH1,  B3GN61,  CDH1-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM