DISEASES

Disease-gene associations mined from literature

Literature associating TNFRSF13B and immunoglobulin alpha deficiency

TNFRSF13B [ENSP00000261652]

Tumor necrosis factor receptor superfamily, member 13B; Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity; CD molecules

Synonyms:  TNFRSF13B,  E7ER05,  J3QR67,  O14836,  Q4ACX1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM