Disease-gene associations mined from literature

Literature associating LPIN2 and hereditary mixed polyposis syndrome 2

LPIN2 [ENSP00000261596]

Phosphatidate phosphatase LPIN2; Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity); Lipins

Synonyms:  LPIN2,  LPIN2p,  hLPIN2,  J3KTK1,  J3QQN0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM