DISEASES

Disease-gene associations mined from literature

Literature associating VWF and hemorrhagic disease

VWF [ENSP00000261405]

Von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma; Endogenous ligands

Synonyms:  VWF,  H2DLA2,  I3L4K4,  P04275,  VWF-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM