Literature associating VWF and thrombocytopenia due to platelet alloimmunization
VWF [ENSP00000261405]
Von Willebrand antigen 2; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Synonyms: VWF, I3L4K4, P04275, I3L4K4p, hI3L4K4 ...