DISEASES

Disease-gene associations mined from literature

Literature associating SNCAIP and Lewy body dementia

SNCAIP [ENSP00000261368]

Synuclein, alpha interacting protein; Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1; Ankyrin repeat domain containing

Synonyms:  SNCAIP,  B7Z616,  D6R9G8,  D6RBR2,  D6RD29 ...

Linkouts:  STRING  Pharos  UniProt  OMIM