DISEASES

Disease-gene associations mined from literature

Literature associating PEBP1 and anus benign neoplasm

PEBP1 [ENSP00000261313]

Phosphatidylethanolamine binding protein 1; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.

Synonyms:  PEBP1,  PEBP1p,  hPEBP1,  D9IAI1,  HEL-210 ...

Linkouts:  STRING  Pharos  UniProt  OMIM