DISEASES

Disease-gene associations mined from literature

Literature associating PREB and testicular leukemia

PREB [ENSP00000260643]

Mammalian guanine nucleotide exchange factor mSec12; Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER; WD repeat domain containing

Synonyms:  PREB,  B5MC98,  F8WCS5,  H7BZX0,  Q05DB2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM