DISEASES

Disease-gene associations mined from literature

Literature associating POU5F1 and adhesions of uterus

POU5F1 [ENSP00000259915]

POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Synonyms:  POU5F1,  POU5F1p,  hPOU5F1,  OCT3,  OCT4 ...

Linkouts:  STRING  Pharos  OMIM