DISEASES

Disease-gene associations mined from literature

Literature associating GCM1 and gestational choriocarcinoma

GCM1 [ENSP00000259803]

Chorion-specific transcription factor GCMa; Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta- specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development.

Synonyms:  GCM1,  GCM1p,  hGCM1,  Q9NP62,  GCMA ...

Linkouts:  STRING  Pharos  UniProt  OMIM