DISEASES

Disease-gene associations mined from literature

Literature associating IL1RN and osteomyelitis

IL1RN [ENSP00000259206]

Interleukin-1 receptor antagonist protein; Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure; Endogenous ligands

Synonyms:  IL1RN,  IL1RNp,  hIL1RN,  A0A024R528,  IL-1RA3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM