Literature associating MTHFS and autosomal dominant cutis laxa 3
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase); Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate.
Synonyms: MTHFS, H3BN04, P49914, Q96EE9, H3BN04p ...