Disease-gene associations mined from literature

Literature associating BACH2 and immunodeficiency 60

BACH2 [ENSP00000257749]

BTB and CNC homology 1, basic leucine zipper transcription factor 2; Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin (By similarity); BTB domain containing

Synonyms:  BACH2,  BACH2p,  hBACH2,  Q7Z6Q0,  Q9BYV9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM