Literature associating KLB and hepatocellular clear cell carcinoma
Klotho beta-like protein; Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Synonyms: KLB, Q86Z14, Q86Z14p, hQ86Z14, 152831 ...