DISEASES

Disease-gene associations mined from literature

Literature associating FOLH1 and malignant epithelioid hemangioendothelioma

FOLH1 [ENSP00000256999]

Folate hydrolase (prostate-specific membrane antigen) 1; Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

Synonyms:  FOLH1,  FOLH1p,  hFOLH1,  FOLH1B,  E9PI29 ...

Linkouts:  STRING  Pharos  UniProt  OMIM