Literature associating KRAS and ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3
Kirsten rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner; Belongs to the small GTPase superfamily. Ras family.
Synonyms: KRAS, A0A024RAV5, G3V4K2, G3V5T7, I1SRC5 ...