Disease-gene associations mined from literature

Literature associating KRAS and pre-malignant neoplasm

KRAS [ENSP00000256078]

Kirsten rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner; Belongs to the small GTPase superfamily. Ras family.

Synonyms:  KRAS,  A0A024RAV5,  G3V4K2,  G3V5T7,  I1SRC5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM