DISEASES

Disease-gene associations mined from literature

Literature associating ACTR3B and distal hereditary motor neuronopathy type 1

ACTR3B [ENSP00000256001]

ARP3 actin-related protein 3 homolog B (yeast); Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors; Actin related proteins

Synonyms:  ACTR3B,  ACTR3Bp,  hACTR3B,  B3KM55,  Q9P1U1 ...

Linkouts:  STRING  Pharos  UniProt