DISEASES

Disease-gene associations mined from literature

Literature associating PEMT and neuronal ceroid lipofuscinosis

PEMT [ENSP00000255389]

Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.

Synonyms:  PEMT,  D3YTC7,  J3KTR2,  J3QLU8,  Q9UBM1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM