Disease-gene associations mined from literature

Literature associating JAG1 and primary sclerosing cholangitis

JAG1 [ENSP00000254958]

Protein jagged-1; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling . May be involved in cell-fate decisions during hematopoiesis . Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

Synonyms:  JAG1,  JAG1p,  hJAG1,  A0A087WXH5,  A0A087X1E8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM