Literature associating JAG1 and primary sclerosing cholangitis
Protein jagged-1; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro); CD molecules
Synonyms: JAG1, JAG1p, hJAG1, B4DYR1, B7U6M8 ...