Disease-gene associations mined from literature

Literature associating IGJ and immunoglobulin alpha deficiency

IGJ [ENSP00000254801]

Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.

Synonyms:  IGJ,  C9JA05,  D6RD17,  D6RHJ6,  JCHAIN ...

Linkouts:  STRING  Pharos  UniProt  OMIM