Literature associating G6PC and severe congenital neutropenia 4
G6PC [ENSP00000253801]
Glucose-6-phosphatase, catalytic subunit; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels; Belongs to the glucose-6-phosphatase family.
Synonyms: G6PC, G6PCp, hG6PC, A0A024R1U9, K7ELS6 ...