Literature associating MYOD1 and spindle cell rhabdomyosarcoma
Class C basic helix-loop-helix protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
Synonyms: MYOD1, MYOD1p, hMYOD1, P15172, BHLHC1 ...