Disease-gene associations mined from literature

Literature associating RAC2 and food allergy

RAC2 [ENSP00000249071]

Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.

Synonyms:  RAC2,  RAC2p,  hRAC2,  A0A024R1P2,  B1AH77 ...

Linkouts:  STRING  Pharos  UniProt  OMIM