Literature associating HSPB1 and Charcot-Marie-Tooth disease
Estrogen-regulated 24 kDa protein; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.
Synonyms: HSPB1, HSPB1p, hHSPB1, C9J3N8, F8WE04 ...