Literature associating TAS2R4 and cerebellar ataxia type 9
Taste receptor, type 2, member 4; Gustducin-coupled receptor for denatonium and N(6)- propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
Synonyms: TAS2R4, TAS2R4p, hTAS2R4, HOSA(ADYGEI)-T2R4, HOSA(BIAKA)-T2R4 ...