Disease-gene associations mined from literature

Literature associating MLX and olfactory groove meningioma

MLX [ENSP00000246912]

Class D basic helix-loop-helix protein 13; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation; Basic helix-loop-helix proteins

Synonyms:  MLX,  K7EID0,  MLX-001,  MLX-002,  MLX-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM