Disease-gene associations mined from literature

Literature associating C3 and glomerulonephritis

C3 [ENSP00000245907]

Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.

Synonyms:  C3,  C3p,  hC3,  HEL-S-62p,  M0QXZ3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM