Disease-gene associations mined from literature

Literature associating C3 and glomerulonephritis

C3 [ENSP00000245907]

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates; C3 and PZP like, alpha-2-macroglobulin domain containing

Synonyms:  C3,  C3p,  hC3,  HEL-S-62P,  M0QYC8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM