Disease-gene associations mined from literature

Literature associating CLPP and learning disability

CLPP [ENSP00000245816]

Caseinolytic mitochondrial matrix peptidase proteolytic subunit; Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates; Belongs to the peptidase S14 family.

Synonyms:  CLPP,  A4UCS4,  M0QXE9,  M0QYV5,  M0R208 ...

Linkouts:  STRING  Pharos  UniProt  OMIM