DISEASES

Disease-gene associations mined from literature

Literature associating LILRB3 and Takayasu's arteritis

LILRB3 [ENSP00000245620]

Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B- cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM); CD molecules

Synonyms:  LILRB3,  LILRB3p,  hLILRB3,  O75022,  ILT5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM