DISEASES

Disease-gene associations mined from literature

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Literature associating CEACAM8 and paroxysmal nocturnal hemoglobinuria

CEACAM8 [ENSP00000244336]

Carcinoembryonic antigen-related cell adhesion molecule 8; Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 . Heterophilic interaction with CEACAM8 occurs in activated neutrophils ; Belongs to the immunoglobulin superfamily. CEA family.

Synonyms:  CEACAM8,  CEACAM8p,  hCEACAM8,  M0R1X3,  P31997 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.