DISEASES

Disease-gene associations mined from literature

Literature associating C4BPB and patellar tendinitis

C4BPB [ENSP00000243611]

Complement component 4 binding protein, beta; Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S; Sushi domain containing

Synonyms:  C4BPB,  C4BPBp,  hC4BPB,  P20851,  Q5VVQ7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM