DISEASES

Disease-gene associations mined from literature

Literature associating SEC61A1 and Buruli ulcer disease

SEC61A1 [ENSP00000243253]

Protein transport protein Sec61 subunit alpha isoform 1; Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity); Belongs to the SecY/SEC61-alpha family.

Synonyms:  SEC61A1,  SEC61A1p,  hSEC61A1,  B3KME8,  B3KNF6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM