DISEASES

Disease-gene associations mined from literature

SearchDownloadsAbout

Literature associating NEUROG3 and proprotein convertase 1/3 deficiency

NEUROG3 [ENSP00000242462]

Class A basic helix-loop-helix protein 7; Acts as a transcriptional regulator. Together with NKX2- 2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity); Basic helix-loop-helix proteins

Synonyms:  NEUROG3,  NEUROG3p,  hNEUROG3,  E0X9P2,  Q9Y4Z2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.