Literature associating RHOQ and progressive familial heart block type II
Rho-related GTP-binding protein RhoQ; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia; Rho family GTPases
Synonyms: RHOQ, E5RFZ3, F8WET9, H0YB40, HEL-S-42 ...