Literature associating FGF23 and bone disease
Tumor-derived hypophosphatemia-inducing factor; Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
Synonyms: FGF23, FGF23p, hFGF23, Q9GZV9, HYPF ...