DISEASES

Disease-gene associations mined from literature

Literature associating TNP1 and epididymis disease

TNP1 [ENSP00000236979]

Transition protein 1 (during histone to protamine replacement); Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction; Belongs to the nuclear transition protein 1 family.

Synonyms:  TNP1,  TNP1p,  hTNP1,  P09430,  Q4ZG82 ...

Linkouts:  STRING  Pharos  UniProt  OMIM