DISEASES

Disease-gene associations mined from literature

Literature associating CTSD and bone chondrosarcoma

CTSD [ENSP00000236671]

Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease; Cathepsins

Synonyms:  CTSD,  C9JH19,  F8W787,  F8WD96,  H7C1V0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM