Literature associating CLCA1 and chronic obstructive pulmonary disease
Calcium-activated chloride channel family member 1; May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC; Chloride channel accessory
Synonyms: CLCA1, CLCA1p, hCLCA1, A8K7I4, CLCA1-001 ...