Disease-gene associations mined from literature

Literature associating ODC1 and secondary progressive multiple sclerosis

ODC1 [ENSP00000234111]

Ornithine decarboxylase 1; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis; Belongs to the Orn/Lys/Arg decarboxylase class-II family.

Synonyms:  ODC1,  ODC1p,  hODC1,  C9JG30,  P11926 ...

Linkouts:  STRING  Pharos  UniProt  OMIM